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Quantitative genetic analysis of biobehavioral markers of aging in Swedish studies of adult twins
Author(s)Deborah Finkel, Nancy L Pedersen, Stig Berg
Journal titleJournal of Aging and Health, vol 12, no 1, February 2000
Pagespp 47-68
KeywordsBiological ageing ; Twins ; Mental health [elderly] ; Measurement ; Sweden.
AnnotationThere has been much interest in identifying markers of ageing as an alternative to chronological age. Many gerontologists believe that a variety of ages exist in the same individual, and that multiple patterns of age-related changes can be identified. Functional age (also referred to as biological age) is used by some gerontologists to represent the ageing process in a meaningful way, instead of relying on chronological age. This study examines the generalisability of markers of ageing across samples and cultures and the genetic and environmental influences on them. As part of two studies, 18 demographic, cognitive, physiological, personality, and behavioural variables were available from 459 Swedish twin pairs ranging in age from 40 to 90. Twelve markers of ageing were identified using stepwise regression. Factor analysis of the markers produced 4 factors: general knowledge, fluid abilities, cardiovascular functioning, and well-being. The results indicate that one ageing theory cannot account for changes in all markers of ageing. Ageing of various systems occurs as a result of different combinations of genetic and environmental influences. (RH).
Accession NumberCPA-000515003 A
ClassmarkBH: SVR: D: 3R: 76P

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