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Application of a growth curve approach to modeling the progression of Alzheimer's disease
Author(s)Yaakov Stern, Xinhua Liu, Marilyn Albert, Jason Brandt
Journal titleThe Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol 51A, no 4, July 1996
Pagespp M179-M184
KeywordsDementia ; Mathematical models ; Statistical distributions.
AnnotationChanges in measures of clinical severity of Alzheimer's disease over time were modelled, using data from the Modified Mini-Mental State Examination (MMSE) and measures of basic and instrumental ADL, administered semi-annually for up to 5 years to patients with probable AD. Differences in patterns of progression of these measures have implications for predicting disease course in AD and the planning of clinical trials.
Accession NumberCPA-961021009 A
ClassmarkEA: 3LM: 3Y3

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