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Centre for Policy on Ageing | |
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| The association of weight change in Alzheimer's disease with severity of disease and mortality: a longitudinal analysis | | Author(s) | Heidi White, Carl Pieper, Ken Schmader |
| Journal title | Journal of the American Geriatrics Society, vol 46, no 10, October 1998 |
| Pages | pp 1223-1227 |
| Keywords | Dementia ; Nutrition ; Malnutrition ; Weight ; Death ; Longitudinal surveys ; United States of America. |
| Annotation | Weight loss is a common problem in Alzheimer's disease (AD), yet the relationship is poorly understood. This study aimed to examine weight loss in relation to the severity of AD, to identify confounders that might account for weight loss, and to investigate the association of weight change with mortality. The study included 666 subjects with AD from the Consortium to Establish a Registry for Alzheimer's Disease (CERAD), a longitudinal study of AD subjects. The findings showed that weight loss in AD was associated with severity and progression of disease. Each change in stage of AD was associated with an estimated average weight loss of nearly 2 lb. The correlation between change in stage of AD and weight change was statistically significant, which indicates a greater tendency toward weight loss with progression of AD. Weight loss of _ 5% in any year before death was a significant predictor of mortality. In contrast, weight gain decreased the risk of mortality. (AKM). |
| Accession Number | CPA-981118409 A |
| Classmark | EA: CF: CSM: 4X6: CW: 3J: 7T |
Data © Centre for Policy on Ageing |
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| ...from the Ageinfo database published by Centre for Policy on Ageing. |
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